ANTIOXIDANT STUDIES OF SOME SYNTHETIC CURCUMINOIDS

Abstract

The antioxidant activity of eight curcuminoid analogues (HL1 to HL8 ) was studied by thiocyanate method. The results revealed that the antioxidant property depends on the nature of aryl substituents and the extent of conjugation present in the compounds. A comparison of the observed antioxidant and reported antitumour activities of these synthetic curcuminoids revealed that compounds having highest antitumour activity also exhibited maximum antioxidant activity.